Pelvic organ prolapse (POP) is a condition where there is bulging of one or more of the pelvic organs into the vagina.It occurs due to a weakening of the tissues that support the pelvic organs. POP is a common condition and is experienced by many women, particularly after childbirth.
Women who suffer POP are often treated with synthetic polypropylene and biological mesh to hold the prolapsed organs in place. This same mesh is also used to treat stress urinary incontinence (SUI) and hernias.
Most patients who have the mesh inserts respond well to the treatment. However, a report published by the Medicines and Healthcare products Regulatory Agency in October 2014 underlined that a rising number of adverse reactions were being reported by patients using these products.
These adverse effects included:
- pain – includes any reference given to post-operative pain
- extrusion/erosion – refers to incidents where the mesh has either migrated or become partially exposed through vaginal tissue. It does not refer to the mesh eroding or fraying.
- infection – references to post-operative infection, and for example any recurring urinary tract infection
- relapse of conditions/urinary symptoms – reoccurrence of urinary incontinence
- Perforation of organ – refers to incidents that were procedural related, such as perforation of the bladder or bowel when inserting the mesh implant.
- sexual difficulties – dyspareunia, painful sexual intercourse
- Implanting of transvaginal tape or surgical mesh
- Gynecare Prolift and Prolift +M, TVT, Obturator System, Secur and Prosima
- Gynemesh and Prolene, all manufactured by Ethicon
- Boston Scientific Obtryx Transobturator Tape (TOT)
- Bard Avaulta mesh
- Endo Health Solutions Perigee, Apogee and Elevate transvaginal meshes
- Coloplast mesh products